Association between psoriasis vulgaris and myasthenia gravis
DOI:
https://doi.org/10.47196/da.v31i2.2868Keywords:
psoriasis, myasthenia gravis, IL-17Abstract
The association between psoriasis vulgaris and myasthenia gravis is rare. Both pathologies are autoimmune, chronic and share the mechanism of T-lymphocyte-dependent inflammation and IL-17 production. Two clinical cases are presented below that started with psoriasis vulgaris with subsequent onset of myasthenia gravis. One of them underwent treatment with an anti- IL-17 antibody which led to elimination of psoriatic lesions and remission of myasthenic symptoms, supporting the role of IL-17 cytokines in the pathogenesis of both diseases.
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