Restrospective study of 25 patients with DRESS syndrome
DOI:
https://doi.org/10.47196/da.v29i2.2452Keywords:
adverse reaction to drugs, DRESS, pharmacodermaAbstract
DRESS syndrome is an acronym for drug reaction with eosinophilia and systemic symptoms, it is considered a rare and severe disease characterized by the presence of eosinophilia that comes with exanthema, facial edema, fever, lymphadenopathy, and liver compromise. It typically has a long evocative delay time. The medicines commonly involved are anticonvulsants, allopurinol, and antibiotics. Treatment consists of suspending the associated medication and, depending on the severity of skin and internal organ involvement, the use of corticosteroids. We conducted a descriptive, retrospective, and observational study of 25 clinical cases diagnosed with DRESS syndrome who were admitted to the Dr. Federico Abete Trauma and Emergency Hospital between June 2013 and November 2022. Clinical characteristics, drugs involved, and required treatment are described. Finally, a bibliographical review of the subject was developed. The search engines used were: Medline, Lilacs, Clinicalkey and Google Scholar.
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