Idiopathic granulomatous mastitis and erythema nodosum as extramamary manifestation

Authors

  • Florencia De Lena San Roque Hospital, Gonnet, Province of Buenos Aires, Argentina
  • María Victoria Itatí Cordo San Roque Hospital, Gonnet, Province of Buenos Aires, Argentina
  • Irene Sorokin San Roque Hospital, Gonnet, Province of Buenos Aires, Argentina
  • Fabricio Torchiari San Roque Hospital, Gonnet, Province of Buenos Aires, Argentina
  • Rocío Raffaeli San Roque Hospital, Gonnet, Province of Buenos Aires, Argentina

DOI:

https://doi.org/10.47196/da.v29i3.2416

Keywords:

idiopathic granulomatous mastitis, erythema nodosum

Abstract

Idiopathic granulomatous mastitis (IGM) is a rare and benign inflammatory disease of the breast of unknown etiology and challenging to diagnose. Clinically it mimics other pathologies, such as infectious mastitis and breast carcinoma, and histologically it resembles other inflammatory granulomatous conditions. Diagnosis is made through biopsy and exclusion of other granulomatous conditions. Sometimes it can present erythema nodosum (EN) as an extramammary manifestation. Treatment is complex and with a high probability of recurrence. We present the case of a woman with IGM associated with EN with an excellent response to the established treatment.

Author Biographies

Florencia De Lena, San Roque Hospital, Gonnet, Province of Buenos Aires, Argentina

Dermatologist Fellow, Dermatology Room

María Victoria Itatí Cordo, San Roque Hospital, Gonnet, Province of Buenos Aires, Argentina

Staff Physician, Dermatology Room

Irene Sorokin, San Roque Hospital, Gonnet, Province of Buenos Aires, Argentina

Staff Physician, Dermatology Room

Fabricio Torchiari, San Roque Hospital, Gonnet, Province of Buenos Aires, Argentina

Anatomopathologist, Pathological Anatomy Service, Dermatology Room

Rocío Raffaeli, San Roque Hospital, Gonnet, Province of Buenos Aires, Argentina

Head of Dermatology Ward

References

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II. Jiménez-González M, Melero-López A, Sánchez-Gabaldon R. Mastitis granulomatosa. Clin Invest Gin Obst. 2015;42:141-144.

III. Lucas R, Gussman D, Polis RL, Rattigan MI, et ál. Idiopathic granulomatous mastitis with erythema nodosum simulating breast abscess in pregnancy: a case report. Obstet Med. 2014;7:37-39.

IV. Parperis K, Achilleos S, Costi E, Vardas M. Granulomatous mastitis, erythema nodosum and arthritis syndrome: case-based review. Rheumatol Int. 2021;41:1175-1181.

V. Marín-Hernández C, Piñero-Madrona A, Gil-Vázquez PJ, Galindo-Fernández PJ, et ál. Mastitis granulomatosa idiopática. Una rara entidad benigna que puede simular un cáncer de mama. Cir Esp. 2018;96:173-180.

VI. Al-Khaffaf BH, Shanks JH, Bundred N. Erythema nodosum an extramammary manifestation of granulomatous mastitis. Breast J. 2006;12:569-570.

VII. Adams DH, Hubscher SG, Scott DG. Granulomatous mastitis a rare cause of erythema nodosum. Postgrad Med J. 1987;63:581-582.

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Published

2023-12-01

Issue

Vol. 29 No. 3 (2023): September-December

Section

Clinical Cases

License

Copyright (c) 2023 on behalf of the authors. Reproduction rights: Argentine Society of Dermatology

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