Transition from pemphigus foliaceus to pemphigus vulgaris confirmed by ELISA

Authors

DOI:

https://doi.org/10.47196/da.v30i1.2391

Keywords:

ELISA, pemphigus vulgaris, pemphigus foliaceus, transition

Abstract

Pemphigus is an autoimmune bullous disease mediated by autoantibodies against desmosome components, mainly desmoglein 1 and/or 3. The two main subtypes are pemphigus vulgaris and non-endemic pemphigus foliaceus, with distinctive clinical, histopathological, and immunological features. The shift or transition between these subtypes is an infrequent event, which physiopathology remains unclear. We communicate the cases of a patient with non-endemic pemphigus foliaceous that shifted to pemphigus vulgaris with serological confirmation through ELISA technique. This represents the most unusual type of phenotypical transition in patients with pemphigus.

Author Biographies

Margarita Muñoz de Toro, Francisco Javier Muñiz Infectious Diseases Hospital, Autonomous City of Buenos Aires, Argentina

Dermatologist, Excursionist, Dermatology Service

Maria Emilia Candiz, Francisco Javier Muñiz Infectious Diseases Hospital, Autonomous City of Buenos Aires, Argentina

Dermatologist, Dermatology Service, 

Olga Lucía Forero, Francisco Javier Muñiz Infectious Diseases Hospital, Autonomous City of Buenos Aires, Argentina

Dermatologist, Dermatology Service

Liliana Olivares, Francisco Javier Muñiz Infectious Diseases Hospital, Autonomous City of Buenos Aires, Argentina

Dermatologist, Former Head of the Service, Dermatology Service

Esteban Maronna, Francisco Javier Muñiz Infectious Diseases Hospital, Autonomous City of Buenos Aires, Argentina

Pathologist, Pathology Service

References

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Published

2024-04-01

Issue

Vol. 30 No. 1 (2024): January-April

Section

Clinical Cases

License

Copyright (c) 2024 Argentine Society of Dermatology

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