Hypersensitivity to exogenous progestogens

Authors

  • Mercedes Costantino Zanchin Interzonal Hospital Specialized in Acute and Chronic San Juan de Dios de La Plata, La Plata, Province of Buenos Aires, Argentina
  • María Eugenia Amoreo Interzonal Hospital Specialized in Acute and Chronic San Juan de Dios de La Plata, La Plata, Province of Buenos Aires, Argentina
  • Mariana Emilia Bernardo Interzonal Hospital Specialized in Acute and Chronic San Juan de Dios de La Plata, La Plata, Province of Buenos Aires, Argentina
  • Lucía María Córdoba Interzonal Hospital Specialized in Acute and Chronic San Juan de Dios de La Plata, La Plata, Province of Buenos Aires, Argentina
  • María Alejandra Verea Interzonal Hospital Specialized in Acute and Chronic San Juan de Dios de La Plata, La Plata, Province of Buenos Aires, Argentina

DOI:

https://doi.org/10.47196/da.v29i1.2361

Keywords:

progestogen Hypersensitivity, pregnancy and puerperium dermatosis

Abstract

Progesterone hypersensitivity is a heterogeneous clinical entity with pathophysiology, diagnostic and treatment challenges. Its presentation is associated with increased endogenous progesterone in the luteal phase of the menstrual cycle, in pregnancy or with the administration to exogenous progestogens. With an increasing prevalence, which may be due to the increasing use of medical treatments that generate greater exposure to supraphysiological doses of this hormone, we present the patient's clinical case, who during a distant puerperium and 72hs after the application of Medroxyprogesterone acetate developed erythematous-violaceous plaque and urticarial lesions on the buttocks and thighs.

Author Biographies

Mercedes Costantino Zanchin, Interzonal Hospital Specialized in Acute and Chronic San Juan de Dios de La Plata, La Plata, Province of Buenos Aires, Argentina

Resident Physician, Dermatology Service

 

María Eugenia Amoreo, Interzonal Hospital Specialized in Acute and Chronic San Juan de Dios de La Plata, La Plata, Province of Buenos Aires, Argentina

Resident Physician, Dermatology Service

Mariana Emilia Bernardo, Interzonal Hospital Specialized in Acute and Chronic San Juan de Dios de La Plata, La Plata, Province of Buenos Aires, Argentina

Chief Resident, Dermatology Service

Lucía María Córdoba, Interzonal Hospital Specialized in Acute and Chronic San Juan de Dios de La Plata, La Plata, Province of Buenos Aires, Argentina

Dermatologist. Resident Instructor, Dermatology Service

María Alejandra Verea, Interzonal Hospital Specialized in Acute and Chronic San Juan de Dios de La Plata, La Plata, Province of Buenos Aires, Argentina

Head of Service, Dermatology Service

References

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Published

2023-04-11

Issue

Vol. 29 No. 1 (2023): January/April 2023

Section

Clinical Cases

License

Copyright (c) 2023 on behalf of the authors. Reproduction rights: Argentine Society of Dermatology

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

El/los autor/es tranfieren todos los derechos de autor del manuscrito arriba mencionado a Dermatología Argentina en el caso de que el trabajo sea publicado. El/los autor/es declaran que el artículo es original, que no infringe ningún derecho de propiedad intelectual u otros derechos de terceros, que no se encuentra bajo consideración de otra revista y que no ha sido previamente publicado.

 

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