Myths and truths. About acne
DOI:
https://doi.org/10.47196/da.v28i1.2298Keywords:
acneAbstract
Dietary supplements based on whey proteins are widely consumed by young athletes with the aim of increasing muscle mass. There is pathophysiological evidence that they promote the appearance of acne by elevating postprandial plasma levels of postprandial insulin and basal insulin-like growth factor-1 (IGF-1). This leads to the reduction of the transcription factor FoxO1, a key regulator of target genes involved in the pathology. Its deficiency has been linked to major acne triggers such as activation of androgen receptors, comedogenesis, increased sebaceous lipogenesis and follicular inflammation.
References
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II. Arias MI, Adame GJ, Moreno J, Kaminsky A. Relación entre dieta y acné en pacientes de Iberoamérica. Dermatol Rev Mex. 2021;65:22-32. 2. Claudel JP, Auffret N, Leccia MT, Poli F, et ál. Acne and nutrition: hypotheses, myths and facts. J Eur Acad Dermatol Venereol.2018;32:1631-1637.
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