Cryptococcosis secondary to immunosuppression in a patient with autoimmune hepatitis

Authors

  • Victoria Catalina Mardon General Hospital for Acute Dr. Cosme Argerich, Autonomous City of Buenos Aires, Argentina
  • Mariana Arias General Hospital for Acute Dr. Cosme Argerich, Autonomous City of Buenos Aires, Argentina
  • Florencia Quadrana General Hospital for Acute Dr. Cosme Argerich, Autonomous City of Buenos Aires, Argentina
  • Carla Trila General Hospital for Acute Dr. Cosme Argerich, Autonomous City of Buenos Aires, Argentina
  • Alejandra Abeldaño University of Buenos Aires, General Hospital for Acute Dr. Cosme Argerich, Autonomous City of Buenos Aires, Argentina

DOI:

https://doi.org/10.47196/da.v28i2.2217

Keywords:

secondary cutaneous cryptococcosis, non-HIV immunosuppression, autoimmune hepatitis, amphotericin, fluconazole

Abstract

Cryptococcosis is a worldwide-distributed fungal infection that usually occurs in immunocompromised patients, especially whit HIV. It most frequently affects lung and central nervous system, being the skin manifestations uncommon. Diagnosis is made by direct observation, histopathological studies, culture isolation and the presence of capsular antigen in blood or cerebrospinal fluid. Therapeutics will depend on how the infection is present and the degree of immunological compromiso at the time of contact with the fungus. We present a case of a patient whit history of autoimmune hepatitis who presented cutaneous cryptococcosis due to hematogenic disseminate skin, with good response to the established therapeutic.

Author Biographies

Victoria Catalina Mardon, General Hospital for Acute Dr. Cosme Argerich, Autonomous City of Buenos Aires, Argentina

Dermatologist

Mariana Arias, General Hospital for Acute Dr. Cosme Argerich, Autonomous City of Buenos Aires, Argentina

Dermatologist

Florencia Quadrana, General Hospital for Acute Dr. Cosme Argerich, Autonomous City of Buenos Aires, Argentina

Dermatologist

Carla Trila, General Hospital for Acute Dr. Cosme Argerich, Autonomous City of Buenos Aires, Argentina

Medical Anatomopathologist

Alejandra Abeldaño, University of Buenos Aires, General Hospital for Acute Dr. Cosme Argerich, Autonomous City of Buenos Aires, Argentina

Head of the Dermatology Unit. Associate Professor, University of Buenos Aires, General Hospital for Acute Dr. Cosme Argerich, Autonomous City of Buenos Aires

References

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Published

2022-06-01

Issue

Section

Clinical Cases