Calciphylaxis

Authors

  • Fabiana Cergneux Esquel Zonal Hospital, Chubut, Argentina
  • Agustín Dal Verme Esquel Zonal Hospital, Chubut, Argentina
  • Lorna Austin Esquel Zonal Hospital, Chubut, Argentina
  • Georgina Baroffio Esquel Zonal Hospital, Chubut, Argentina
  • Karina Lewis Esquel Zonal Hospital, Chubut, Argentina

DOI:

https://doi.org/10.47196/da.v27i4.2176

Keywords:

calciphylaxis, calcifying uremic arteriolopathy, chronic renal failure

Abstract

Calciphylaxis or calcifying uremic arteriolopathy is a rare disease that carries high morbidity and mortality between 40% and 80%. It is produced by calcification of small caliber vessels and mainly affects patients with chronic renal failure. It usually begins with a change in skin color and then ulceration, pain and skin necrosis occur.

We present a 70-year-old man with chronic renal failure who developed painful skin lesions on his lower limbs.

Author Biographies

Fabiana Cergneux, Esquel Zonal Hospital, Chubut, Argentina

Medical Specialist in Dermatology

Agustín Dal Verme, Esquel Zonal Hospital, Chubut, Argentina

Physician Specialist in Medical Clinic

Lorna Austin, Esquel Zonal Hospital, Chubut, Argentina

Medical Specialist in Dermatology

Georgina Baroffio, Esquel Zonal Hospital, Chubut, Argentina

Medical Specialist in Dermatology

Karina Lewis, Esquel Zonal Hospital, Chubut, Argentina

Medical Pathologist

References

I. Bertera A, Tabar J, Díaz P, García S, et ál. Tratamiento de la arteriolopatía calcificante urémica con tiosulfato de sodio intravenoso. Dermatol Argent. 2018;24:205-207.

II. Batún Garrido JA, Hernández Nuñez E, Muñoz Pérez H. Calcifilaxis en la práctica clínica: informe de un caso con insuficiencia renal crónica terminal. Med Int Méx. 2014;30:721-726.

III. Rotman JA, Dean KE, Magro C, Nuovo G, et ál. Concomitant calciphylaxis and COVID-19 associated thrombotic retiform purpura. Skeletal Radiol. 2020;49:1879-1884.

IV. Daudén E, Oñate MJ. Calciphylaxis. Dermatol Clin. 2008;26:557-568.

V. Sreedhar A, Sheikh HA, Scagliotti CJ, Nair R. Advanced-stage calciphylaxis: Think before you punch. Cleve Clin J Med. 2016;83:562-564.

VI. Burdorf BT. Calciphylaxis: The potential diagnostic role of radiologists. Radiol Case Rep. 2020;16:415-418.

VII. Mihailescu M, Mehlis S. An unusual case of calciphylaxis in a psoriatic patient without kidney disease. JAAD Case Rep 2021;10:41-43.

VIII. Ruderman I, Toussaint ND, Hawley CM, Krishnasamy R, et ál. The Australian Calciphylaxis Registry: reporting clinical features and outcomes of patients with calciphylaxis. Nephrol Dial Transplant. 2021;36:649-656.

IX. Liu Y, Zhang X, Xie X, Yang X, et ál. Risk factors for calciphylaxis in Chinese hemodialysis patients: a matched case-control study. Ren Fail. 2021;43:406-416.

X. Kodumudi V, Jeha GM, Mydlo N, Kaye AD. Management of cutaneous calciphylaxis. Adv Ther. 2020;37:4797-4807.

Published

2021-12-01