Cryoglobulinemic vasculitis with renal involvement and Sjögren's syndrome
DOI:
https://doi.org/10.47196/da.v26i1.2069Keywords:
Sjögren’s syndrome, Leukocyteclastic vasculitis, Cryoglobulinemic vasculitis, Cryoglobulinemia, Purpura of lower limbs, GlomerulonephritisAbstract
Cryoglobulinemic vasculitis is a small-sized vasculitis that occurs in the context of serum cryoglobulins. Mixed cryoglobulinemias are the most frequent and are associated with chronic infections, typically hepatitis C and autoimmune diseases, most commonly Sjögren's syndrome. Clinical manifestations include purpura of lower limbs, peripheral neuropathy, arthralgias and glomerulonephritis. The presence of cryoglobulinemic vasculitis in the context of Sjögren's syndrome is a marker of poor prognosis. We present the case of a patient with cryoglobulinemic vasculitis associated to cutaneous and renal involvement that led us to the diagnosis of primary Sjögren's syndrome.
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