Estudio de la prevalencia del síndrome metabólico en pacientes con hidradenitis supurativa: Estudio retrospectivo de los últimos 2 años en el Hospital Alejandro Posadas

Jennifer Adriana Guerrero Centeno; Patricia Silvia Della Giovanna

doi:10.47196/da.v26i1.2062

Authors

Jennifer Adriana Guerrero Centeno Dermatology Service, Professor Alejandro Posadas National Hospital, Province of Buenos Aires, Argentina
Patricia Silvia Della Giovanna Faculty of Medicine, University of Buenos Aires, Autonomous City of Buenos Aires, Argentina

DOI:

https://doi.org/10.47196/da.v26i1.2062

Keywords:

Suppurative hidradenitis, Metabolic syndrome

Abstract

Background: Suppurative hidradenitis (SH) is a chronic, inflammatory
disease, closely related to metabolic syndrome (MS), with an increased
risk of cardiovascular comorbidities; for that reason we should keep a
high level of clinical suspicion when one of its components is found.
Objective: To evaluate MS prevalence in patients with diagnosis of SH in
comparison with general population.
Design: Descriptive retrospective study.
Methods: We reviewed clinical and photographical files of patients with
diagnosis of suppurative hidradenitis who consulted from 1/9/2017
until 31/8/2019. Variables analyzed were: sex, age, familial history,
time of evolution, body mass index, abdominal obesity, glycemia, lipid
profile, blood pressure, smoking, number and location of lesions, clinicalechographic severity, response to treatment and clinical evolution.
Results: Thirty patients with SH were evaluated, 23 females and 7
males. The age group between 31-40 years prevailed; of these, 19
patients (63.3%) meet necessary criteria for diagnosis of MS, this
finding did not correlate to the severity degree of SH.
Conclusions: The MS prevalence in our SH patients was 63.3%, compared
to 27.5% in the general population. The importance of this finding lays on
detecting in an early and opportune way, the presence of MS in patients
with SH, and to avoid the risk of future cardiovascular comorbidities.

Author Biographies

Jennifer Adriana Guerrero Centeno, Dermatology Service, Professor Alejandro Posadas National Hospital, Province of Buenos Aires, Argentina

Second Year Resident. Dermatology Service, Posadas Hospital

Patricia Silvia Della Giovanna, Faculty of Medicine, University of Buenos Aires, Autonomous City of Buenos Aires, Argentina

Regular Adjunct Professor of Dermatology, Faculty of Medicine, University of Buenos Aires.

Dermatology Service, Professor Alejandro Posadas National Hospital, Province of Buenos Aires, Argentina.

References

I. Martorell A, García-Martínez FJ, Jiménez-Gallo D, Pascual JC,et ál. Actualización en hidradenitis supurativa (I): epidemiología, aspectos clínicos y definición de severidad de la enfermedad. Actas Dermosifiliogr 2015;106:703-715.

II. Zimman S, Comparatore MV, Vulcano AF, Absi ML, et ál. Hidradenitis supurativa: una aproximación a su prevalencia, características clínicas, comorbilidades y tiempo al diagnóstico, en un hospital universitario de Buenos Aires, Argentina.Actas Dermosifiliogr 2019;110:297-302.

III. Revuz JE, Canoui-Poitrine F, Wolkenstein P, Viallette C, et ál. Prevalence and factors associated with hidradenitis suppurativa: Results from two case-control studies. J Am Acad Dermatol 2008;59:596-601.

IV. Miller IM, Ellervik C, Vinding GR, Zarchi K, et ál. Association of metabolic syndrome and hidradenitis suppurativa. JAMA Dermatol 2014;1501273-1280.

V. Ergun T. Hidradenitis suppurativa and the metabolic syndrome. Clin Dermatol 2018;36:41-47.

VI. Dauden E, Lazaro P, Aguilar MD, Blasco AJ, et ál. Recommendations for the management of comorbidity in hidradenitis suppurativa. J Eur Acad Dermatol Venereol2018;32:129-144.

VII. Miller IM, McAndrew RJ, Hamzavi I. Prevalence, risk factors, and comorbidities of hidradenitis suppurativa.Dermatol Clin 2016;34:7-16.

VIII. Tzellos T, Zouboulis CC, Gulliver W, Cohen AD, et ál. Cardiovascular disease risk factors in patients with hidradenitis suppurativa: a systematic review and meta-analysis of observational studies. Br J Dermatol 2015;173:1142-1155.

IX. García-Valdés L, Flores-Ochoa JF, Vega-Memije ME, ArenasR. Hidrosadenitis supurativa. Parte I. Epidemiología, etiopatogenia, clínica y su diagnóstico. Dermatología CMQ 2017;15:176-183.

X. Díaz A, Espeche W, March C, Flores R,et ál. Prevalencia del síndrome metabólico en Argentina en los últimos 25 años: revisión sistemática de estudios observacionales poblacionales. Hiperten Riesgo Vasc2018:64-69.

XI. Gold DA, Reeder VJ, Mahan MG, Hamzavi IH. The prevalence of metabolic syndrome in patients with hidradenitis suppurativa. J Am Acad Dermatol 2014;70:699-703.

XII. Shalom G, Freud T, Harman-Boehm I, Polishchuk I, et ál. Hidradenitis suppurativa and metabolic syndrome: a comparative cross-sectional study of 3207 patients. Br J Dermatol2015;173:464-470.

XIII. Kromann CB, Deckers IE, Esmann S, Boer J, et ál. Risk factors, clinical course and long-term prognosis in hidradenitis suppurativa: a cross-sectional study. Br J Dermatol2014;171:819-824.

XIV. Garg A, Papagermanos V, Midura M, Strunk A. Incidence of hidradenitis suppurativa among tobacco smokers: a population-based retrospective analysis in the U.S.A. Br J Dermatol 2018;178:709-714.

XV. König A, Lehmann C, Rompel R, Happle R. Cigarette smoking as a triggering factor of hidradenitis suppurativa. Dermatology 1999;198:261-264.