Subcutaneous panniculitis-like T-cell lymphoma in children. Experience in a pediatric hospital
Keywords:
primary cutaneous lymphoma, subcutaneous panniculitis-like T-cell lymphoma, childrenAbstract
76Dermatología Argentina Vol. 24 Nº 2 Junio de 2018: 76-80 ISSN 1515-8411 (impresa) ISSN 1669-1636 (en línea)Linfoma cutáneo T paniculítico en la infancia. Experiencia en un hospital pediátricoSubcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare entity that preferentially involves the subcutaneous tissue and represents < 1% of cutaneous T-cell lymphomas.SPTCL has no predilection of gender and could affect people of all ages but is rarely seen in children.Patients present subcutaneous nodules that affect extremities and trunk but may compromise other locations.Histologically we may observe a diffuse subcutaneous tissue infiltration by atypical lymphocytes arranged around the adipocytes, abundant vacuolated-looking macrophages, fat necrosis and karyorrhexis. Immunohistochemistry and genetic studies are important for diagnosis and prognosis.We present 6 patients diagnosed with SPTCL admitted to our pediatric hospital (Hospital Prof. Dr. Juan Pedro Garrahan) between August 1988 and April 2017.
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