Photoinduced lentiginous acantholytic dermatosis. A new and unusual pattern of Grover`s disease?


  • Ignacio Rebora
  • Osvaldo Stringa
  • Mario Abbruzzese
  • Javier Anaya


Transient acantholytic dermatosis or Grover’s disease, is a dermatosis of unknown aetiology, that typically presents as an erithematous popular eruption with crops of vesicles and crusts over the trunk; in which the most common histopathological finding is the presence of focal acantholysis and dyskeratosis. It affects mostly middle-aged or elderly men. One of the triggering factors most frequently described in the literature is the exposure to sunlight. Four cases have been recently reported of Grover’s disease with a new pattern of clinical presentation,
characterized by inflamed papules and crusts following sun exposure, along with lentiginous “freckling”. They were three middle aged women and a 60 years old man. The histopathological findings coincided in presenting interpapilar ridges elongation associated with focal acantholysis and dyskeratosis. We present a 38 year old female with clinical and histopathological lesions compatible with this new lentiginous pattern of Grover’s disease described by Cooper in 2004

(Dermatol Argent 2010;16(2):122-125).

Keywords: transient acantholytic dermatosis, Grover´s disease, lentiginous, photosensitivity.






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