Atopic dermatitis in adults: observational analysis of 200 patients

Authors

  • Marina Mónaco German Hospital, Private Medical Office of Dermatology (Dr. Prof. Margarita Larralde and Dr. Paula C. Luna), City of Buenos Aires, Argentina
  • Paula Carolina Luna German Hospital, Private Medical Office of Dermatology (Dr. Prof. Margarita Larralde and Dr. Paula C. Luna), City of Buenos Aires, Argentina
  • Cindy Frare German Hospital, City of Buenos Aires, Argentina
  • María Emilia Debernardi German Hospital, City of Buenos Aires, Argentina
  • Luciana Laura Tirelli German Hospital, Private Medical Office of Dermatology (Dr. Prof. Margarita Larralde and Dr. Paula C. Luna), City of Buenos Aires, Argentina
  • Anabel Panizzardi German Hospital, Private Medical Office of Dermatology (Dr. Prof. Margarita Larralde and Dr. Paula C. Luna), City of Buenos Aires, Argentina
  • Margarita Larralde German Hospital, Private Medical Office of Dermatology (Dr. Prof. Margarita Larralde and Dr. Paula C. Luna), City of Buenos Aires, Argentina

DOI:

https://doi.org/10.47196/da.v30i3.2668

Keywords:

atopic dermatitis, eczema, atopy

Abstract

Background: atopic dermatitis (AD) is a chronic inflammatory dermatosis characterized by xerosis, pruritus and eczema. The diagnosis is clinical, and treatment depends on the severity; mild AD is usually controlled with topical medication while moderate/severe AD usually require systemic treatment. It affects most frequently childhood, so studies in adults are limited.

Objectives: describe the epidemiological, clinical characteristics and treatments in adult outpatients with AD.

Design: a retrospective, observational, descriptive and analytical work was carried out.

Materials and methods: demographic, clinical variables, and different treatments were collected from the medical records of patients with AD between 2019 and 2023. The history and associated factors were compared between the types of severity: mild, moderate, and severe.

Results: of the 200 patients, 62.5% were female. 36% had asthma, and 25.5% had rhinitis. Severely ill patients had a higher frequency of asthma and rhinitis. Methotrexate was used more frequently in moderate and severe disease and 24.7% of patients with severe disease required dupilumab.

Conclusions: in our country, research on adult patients with AD is limited. The severity of the disease is more frequently associated with comorbidities. In mild forms of AD, topical treatments were more used, phototherapy was frequent as an intermediate step between moderate and severe forms, and innovative drugs were predominant in severe forms. It is necessary to continue carrying out higher quality studies that evaluate differences in comorbidities and clinical evolution according to the spectrum of severity.

Author Biographies

Marina Mónaco, German Hospital, Private Medical Office of Dermatology (Dr. Prof. Margarita Larralde and Dr. Paula C. Luna), City of Buenos Aires, Argentina

Staff Physician, Dermatology Service

Paula Carolina Luna, German Hospital, Private Medical Office of Dermatology (Dr. Prof. Margarita Larralde and Dr. Paula C. Luna), City of Buenos Aires, Argentina

Staff Physician, Dermatology Service

Cindy Frare, German Hospital, City of Buenos Aires, Argentina

Staff Physician, Dermatology Service

María Emilia Debernardi, German Hospital, City of Buenos Aires, Argentina

Staff Physician, Dermatology Service

Luciana Laura Tirelli, German Hospital, Private Medical Office of Dermatology (Dr. Prof. Margarita Larralde and Dr. Paula C. Luna), City of Buenos Aires, Argentina

Staff Physician, Dermatology Service

Anabel Panizzardi, German Hospital, Private Medical Office of Dermatology (Dr. Prof. Margarita Larralde and Dr. Paula C. Luna), City of Buenos Aires, Argentina

Staff Physician, Dermatology Service

Margarita Larralde, German Hospital, Private Medical Office of Dermatology (Dr. Prof. Margarita Larralde and Dr. Paula C. Luna), City of Buenos Aires, Argentina

Head of the Dermatology Service

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Published

2024-10-21

Issue

Section

Original Articles