Pápulas queratósicas en paciente con insuficiencia renal

María Laura Sanz; María Pía Herlein; Silvana Alejandra León; Graciela Luján Carabajal

doi:10.47196/da.v31i2.2881

Authors

María Laura Sanz Churruca Visca Hospital, City of Buenos Aires, Argentina
María Pía Herlein Churruca Visca Hospital, City of Buenos Aires, Argentina
Silvana Alejandra León Churruca Visca Hospital, City of Buenos Aires, Argentina
Graciela Luján Carabajal Churruca Visca Hospital, City of Buenos Aires, Argentina

DOI:

https://doi.org/10.47196/da.v31i2.2881

Keywords:

keratotic papules, kidney failure, dermatology

Abstract

A 54-year-old male patient with a history of high blood pressure, type 2 diabetes mellitus, and chronic kidney disease, for which he was undergoing hemodialysis, presented to our department with pruritic dermatosis of 3 months' duration. Physical examination revealed numerous hyperpigmented papules and nodules with a keratotic center, measuring 0.3 to 0.7 mm in diameter, located on the back. Symptomatic treatment with antihistamines and emollients was prescribed, and a skin biopsy was performed for histopathological examination. This study revealed central epidermal depression with marked thinning and infiltration of nonspecific eosinophilic fibers. Basophilic debris and a mixed inflammatory infiltrate were observed in the immediately underlying dermis. Using the Masson trichrome staining technique, these fibers stained blue, corresponding to collagen fibers.

Author Biographies

María Laura Sanz, Churruca Visca Hospital, City of Buenos Aires, Argentina

Dermatology Resident Physician

María Pía Herlein, Churruca Visca Hospital, City of Buenos Aires, Argentina

Chief Resident of Dermatology

Silvana Alejandra León, Churruca Visca Hospital, City of Buenos Aires, Argentina

Head of the Dermatology Service

Graciela Luján Carabajal, Churruca Visca Hospital, City of Buenos Aires, Argentina

Staff Physician, Pathological Anatomy Service

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