Keratotic papules on extremities

Authors

  • Valeria Cecilia Orsi J. M. Ramos Mejía General Acute Care Hospital, City of Buenos Aires, Argentina
  • Lola Kuperman Wilder J. M. Ramos Mejía General Acute Care Hospital, City of Buenos Aires, Argentina
  • Griselda María Poppi J. M. Ramos Mejía General Acute Hospital, City of Buenos Aires, Argentina

DOI:

https://doi.org/10.47196/da.v31i2.2880

Keywords:

papules, keratotic, limbs, dermatology

Abstract

A 37-year-old female patient with no relevant medical history presented with xerosis and asymptomatic desquamation of the upper extremities since childhood, which had recently spread to the lower extremities. She reported that her father had similar lesions. Physical examination revealed generalized xerosis, circumscribed keratotic papules and plaques on the hands, forearms, elbows, lower extremities, and feet. A punch biopsy was taken from a keratotic papule located on the left lower extremity. The pathology study revealed epidermis with orthokeratotic hyperkeratosis, regular acanthosis, and church-bell-shaped papillomatosis.

Author Biographies

Valeria Cecilia Orsi, J. M. Ramos Mejía General Acute Care Hospital, City of Buenos Aires, Argentina

Third-year Dermatology Resident

Lola Kuperman Wilder, J. M. Ramos Mejía General Acute Care Hospital, City of Buenos Aires, Argentina

Dermatologist, former Chief Resident

Griselda María Poppi, J. M. Ramos Mejía General Acute Hospital, City of Buenos Aires, Argentina

Dermatopathologist

References

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IV. Reales J, González T, Oronoz M, Civale C, et ál. Acroqueratosis verruciforme de Hopf: a propósito de un caso. Rev Argent Dermatol. 2021;102:56-65.

V. Chapman-Rolle L, De Padova-Elder SM, Ryan E, Kantor GR. Persistent flat-topped papules on the extremities. Acrokeratosis verruciformis of Hopf. Arch Dermatol. 1994;130:508-512.

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Published

2025-08-01

Issue

Vol. 31 No. 2 (2025): May-August

Section

What is your Diagnosis?

License

Copyright (c) 2025 on behalf of the authors. Reproduction rights: Argentine Society of Dermatology

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