Primary anetoderma and antiphospholipid antibodies

Abstract

Abstract
Primary anetoderma is a rare idiopathic disorder of the skin, characterized by circumscribed areas of slack skin, and loss of elastic fibers upon histopathologic examination.
It is occasionally observed in patients with lupus erythematosus or other autoimmune diseases, but has been most consistently associated with antiphospholipid antibodies.
We report two cases of primary anetoderma, both with presence
of anticardiolipin and antiBeta2glicoprotein I antibodies, and one of them with lupus anticoagulant as well. None of the patients fulfill criteria either for systemic lupus erythematosus or antiphospholipid syndrome.
After reviewing the literature, we subscribe to a systematic screening for antiphospholipid antibodies to be performed in each patient with primary anetoderma

(Dermatol Argent 2008;14(5): 372-378

Key words: primary anetoderma; antiphospholipid antibodies; lupus erythematosus; antiphospholipid syndrome.