Lupoid-appearing mucocutaneous leishmaniasis

Authors

  • Paola Zuleta Francisco Javier Muñiz Infectious Diseases Hospital, City of Buenos Aires, Argentina
  • Ludmila Rodríguez Francisco Javier Muñiz Infectious Diseases Hospital, City of Buenos Aires, Argentina
  • Marisa Fernández Francisco Javier Muñiz Infectious Diseases Hospital, City of Buenos Aires, Argentina
  • Clara Corrales Francisco Javier Muñiz Infectious Diseases Hospital, City of Buenos Aires, Argentina
  • Viviana Leiro Francisco Javier Muñiz Infectious Diseases Hospital, City of Buenos Aires, Argentina

DOI:

https://doi.org/10.47196/x3b30326

Keywords:

mucocutaneous leishmaniasis, lupoid leishmaniasis, atypical variants, meglumine antimoniate

Abstract

Leishmaniasis is a zoonotic disease caused by intracellular protozoa of the genus Leishmania spp. We report the case of a 41-year-old female from Tucumán, with a rare presentation of mucocutaneous leishmaniasis (MCL) with lupoid features. Clinical findings included centrofacial plaques with tubercular infiltration and mucosal involvement. Histology showed granulomatous inflammatory infiltrate, and PCR confirmed Leishmania spp. Treatment with meglumine antimoniate plus pentoxifylline was administered, with dose adjustment due to adverse effects, leading to favorable clinical outcome. This case underscores the need to consider lupoid chronic variants in MCL differential diagnosis and highlights the relevance of clinicopathological correlation.

Author Biographies

  • Paola Zuleta, Francisco Javier Muñiz Infectious Diseases Hospital, City of Buenos Aires, Argentina

    Second-year Resident Physician in Dermatology, Dermatology Unit

  • Ludmila Rodríguez, Francisco Javier Muñiz Infectious Diseases Hospital, City of Buenos Aires, Argentina

    Dermatologist, Dermatology Unit

  • Marisa Fernández, Francisco Javier Muñiz Infectious Diseases Hospital, City of Buenos Aires, Argentina

    Infectious Disease Specialist, Dermatology Unit

  • Clara Corrales, Francisco Javier Muñiz Infectious Diseases Hospital, City of Buenos Aires, Argentina

    Medical Pathologist, Dermatology Unit

  • Viviana Leiro, Francisco Javier Muñiz Infectious Diseases Hospital, City of Buenos Aires, Argentina

    Dermatologist, Head of Dermatology Unit

References

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Published

2026-04-28

Issue

Vol. 32 No. 1 (2026): January-april

Section

Clinical Cases

License

Copyright (c) 2026 on behalf of the authors. Reproduction rights: Argentine Dermatology

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