Naltrexone: a possible therapeutic alternative?

Authors

  • Paula Johana Barba Dermatology Service, General Acute Hospital Prof. Dr. Rodolfo Rossi, La Plata, Province of Buenos Aires, Argentina

DOI:

https://doi.org/10.47196/da.v26i1.2063

Keywords:

Naltrexone, Drug

Abstract

Naltrexone is a competitive antagonist drug of classical opioid receptors (µ, d and k), approved in 1984 by the FDA for the treatment of opioid addiction in doses of 50-100 mg. Later, it was also approved and used in the treatment of alcohol dependence.

Author Biography

  • Paula Johana Barba, Dermatology Service, General Acute Hospital Prof. Dr. Rodolfo Rossi, La Plata, Province of Buenos Aires, Argentina

    Dermatologist

References

I. Toljan K, Vrooman B. Low-dose Naltrexone (LDN)-Review of therapeutic utilization. Med Sci (Basel)2018;6:84.

II. Lee B, Elston DM. The uses of naltrexone in dermatologic conditions. J Am Acad Dermatol2019;80:1746-1752.

III. Campbell V, McGrath C, Corry A. Low-dose naltrexone: a novel treatment for Hailey-Hailey disease. Br J Dermatol2018;178:1196-1198.

IV. Jfri A, Litvinov IV, Netchiporouk E. Naltrexone for the treatment of Darier and Hailey-Hailey diseases. J CutanMed Surg2019;23:453-454.

V. Strazzulla LC, Avila L, Lo Sicco K, Shapiro J. Novel treatment using low-dose Naltrexone for lichen planopilaris. J Drugs Dermatol2017;16:1140-1142.

VI. Frech T, Novak K, Revelo MP, Murtaugh M, et ál. Low-dose naltrexone for pruritus in systemic sclerosis. Int JRheumatol2011;2011:804296.

VII. Bridgman AC, Kirchhof MG. Treatment of psoriasis vulgaris using low-dose naltrexone. JAAD Case Rep 2018;4:827-829.

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Published

2020-03-02

Issue

Section

Young Dermatologists