Disseminated fusariosis in a lymphoproliferative syndrome. A report of two cases

Resumen

Abstract:
Disseminated fusariosis is a frequent fungal infection among immunologic dificient patients, most particularly with severe and prolonged neutropenia with onco-hematologic diseases under chemotherapy, or recipients of bone-marrow transplants. The skin manifestations are more common than in other opportunistic mycoses. A bad response to systemic wide-spectrum antifungal drugs is the rule, and high dose liposomal anfotericin B or voriconazol are suggested as alternate systemic treatments.
We report 2 patients with invasive fusariosis in whom the dermatologic lesions were one of the keys leading to the diagnosis of systemic fusariosis with no response to the systemic treatment

(Dermatol Argent 2008;14(3):191-195).

Keywords: disseminated fusariosis, voriconazole, neutropenia