HLA patients with an association of familial lupus-psoriasis
Abstract
Abstract
Lupus and psoriasis are autoimmune diseases of multifactorial etiology, with involvement of genetic and non-genetic factors. The most widely studied genetic factor is Human Leukocyte Antigen (HLA) or Major Histocompatibility Complex in the chromosome 6 region. We report HLA from three generations of patients in the same family with diff erent forms of cutaneous lupus, two of which are associated with psoriasis, and compared the results with seven healthy members of the same family. No HLA found conferred greater susceptibility or protection related to these diseases.
(Dermatol Argent 2009; 15(3):196-189).
Key words: HLA, genetic association, lupus, psoriasis.
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