Histoplasmosis and immune reconstitution syndrome

Authors

  • Julia Raquel Cerono General San Martín Interzonal General Acute Care Hospital, La Plata, Buenos Aires Province, Argentina
  • Mayled Delgado Molina General San Martín Interzonal General Acute Care Hospital, La Plata, Buenos Aires Province, Argentina
  • María Victoria Garritano General San Martín Interzonal General Acute Care Hospital, La Plata, Buenos Aires Province, Argentina
  • Gabriela Laura Arena General San Martín Interzonal General Acute Care Hospital, La Plata, Buenos Aires Province, Argentina

DOI:

https://doi.org/10.47196/ex0rpc26

Keywords:

histoplasmosis, Histoplasma capsulatum, immune reconstitution inflammatory syndrome

Abstract

Histoplasmosis is an endemic mycosis of tropical regions caused by the dimorphic fungus Histoplasma capsulatum. It is one of the most prevalent fungal infections in endemic areas, particularly among patients with HIV. Infection occurs through inhalation of fungal spores, which are found in soil contaminated with bird or bat droppings. This mycosis presents with a wide range of clinical manifestations, from asymptomatic forms to severe and disseminated disease. We present a clinical case of an HIV-positive patient with subacute disseminated histoplasmosis and immune reconstitution inflammatory syndrome.

Author Biographies

  • Julia Raquel Cerono, General San Martín Interzonal General Acute Care Hospital, La Plata, Buenos Aires Province, Argentina

    Second-year Dermatology resident

  • Mayled Delgado Molina, General San Martín Interzonal General Acute Care Hospital, La Plata, Buenos Aires Province, Argentina

    4th-year Dermatology Resident

  • María Victoria Garritano, General San Martín Interzonal General Acute Care Hospital, La Plata, Buenos Aires Province, Argentina

    Head of the Dermatology Ward

  • Gabriela Laura Arena, General San Martín Interzonal General Acute Care Hospital, La Plata, Buenos Aires Province, Argentina

    Head of the Dermatology Department

References

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VIII. Laverde-Sudupe N, Carr ER, Velit-Rios B, Almonte MM, et al. Disseminated histoplasmosis and presumptive CNS toxoplasmosis-associated immune reconstitution inflammatory syndrome in a patient with HIV/AIS: a case report. BCM Infect Dis. 2024. 24:1386.

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Published

2026-07-16

Issue

Vol. 32 No. 2 (2026): May–August

Section

Clinical Cases

License

Copyright (c) 2026 on behalf of the authors. Reproduction rights: Argentine Society of Dermatology

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