Keratotic papules on a patient with chronic kidney disease

Authors

  • María Laura Sanz Churruca Visca Hospital, City of Buenos Aires, Argentina
  • María Pía Herlein Churruca Visca Hospital, City of Buenos Aires, Argentina
  • Silvana Alejandra León Churruca Visca Hospital, City of Buenos Aires, Argentina
  • Graciela Luján Carabajal Churruca Visca Hospital, City of Buenos Aires, Argentina

DOI:

https://doi.org/10.47196/da.v31i2.2881

Keywords:

keratotic papules, kidney failure, dermatology

Abstract

A 54-year-old male patient with a history of high blood pressure, type 2 diabetes mellitus, and chronic kidney disease, for which he was undergoing hemodialysis, presented to our department with pruritic dermatosis of 3 months' duration. Physical examination revealed numerous hyperpigmented papules and nodules with a keratotic center, measuring 0.3 to 0.7 mm in diameter, located on the back. Symptomatic treatment with antihistamines and emollients was prescribed, and a skin biopsy was performed for histopathological examination. This study revealed central epidermal depression with marked thinning and infiltration of nonspecific eosinophilic fibers. Basophilic debris and a mixed inflammatory infiltrate were observed in the immediately underlying dermis. Using the Masson trichrome staining technique, these fibers stained blue, corresponding to collagen fibers.

Author Biographies

  • María Laura Sanz, Churruca Visca Hospital, City of Buenos Aires, Argentina

    Dermatology Resident Physician

  • María Pía Herlein, Churruca Visca Hospital, City of Buenos Aires, Argentina

    Chief Resident of Dermatology

  • Silvana Alejandra León, Churruca Visca Hospital, City of Buenos Aires, Argentina

    Head of the Dermatology Service

  • Graciela Luján Carabajal, Churruca Visca Hospital, City of Buenos Aires, Argentina

    Staff Physician, Pathological Anatomy Service

References

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Published

2025-08-01

Issue

Vol. 31 No. 2 (2025): May-August

Section

What is your Diagnosis?

License

Copyright (c) 2025 on behalf of the authors. Reproduction rights: Argentine Society of Dermatology

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