Angiosarcoma cutáneo

Autores/as

  • Carla Minaudo Hospital Británico de Buenos Aires, Ciudad Autónoma de Buenos Aires, Argentina

Palabras clave:

angiosarcoma cutáneo, angiosarcoma de la piel de la cabeza, angiosarcoma posradioterapia, angiosarcoma asociado a linfedema, síndrome de Stewart-Treves

Resumen

El angiosarcoma (AS) cutáneo es una neoplasia maligna poco frecuente (1,6% de los sarcomas cutáneos) y uno de los tumores de la piel más agresivos y de peor pronóstico. Tiene un origen celular mixto: vascular hemático y linfático. Casi la totalidad de los casos de angiosarcomas cutáneos (ASc) tienen tres patrones de presentación: el angiosarcoma idiopático de la piel de la cabeza (ASpc), el angiosarcoma asociado a linfedema crónico (ASlc) y el angiosarcoma secundario a radioterapia (ASrt). Asimismo, pueden observarse en la piel (con menor frecuencia), AS sobre otros territorios o patologías predisponentes y AS de localización visceral, en los que el compromiso cutáneo puede ser el primer signo para el diagnóstico.Aunque la rareza de esta patología y de sus variantes dificultan esta-blecer un tratamiento unificado, se ha observado una mejor sobrevi-da en los pacientes con terapia multimodal, que combinacirugía con quimioterapia y radioterapia.Entre las novedades terapéuticas se mencionan, por un lado, el uso creci-ente de betabloqueantes como adyuvantes para reducir el volumen tumoral. Por otro lado, la perfusión del miembro aislado se propone como alternativa a la amputación en el síndrome de Stewart-Treves (ST-T).

Biografía del autor/a

Carla Minaudo, Hospital Británico de Buenos Aires, Ciudad Autónoma de Buenos Aires, Argentina

Médica Asistente del Servicio de Dermatología

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Publicado

2018-06-01

Número

Sección

Educación Médica Continua